Evaluation of Efficacy and Sedative Profiles of H1 Antihistamines by Large-Scale Surveillance Using the Visual Analogue Scale (VAS)
Background: H1 antihistamines are widely used as therapeutics for allergic diseases.Sedation is a well-known side effect of H1 antihistamines and sometimes it is life-threatening for patients.Thus it is important to evaluate the sedative properties of H1 antihistamines to avoid side effects.For this purpose, histamine H1 receptor (H1R) occupancy an