EVALUATION OF EFFICACY AND SEDATIVE PROFILES OF H1 ANTIHISTAMINES BY LARGE-SCALE SURVEILLANCE USING THE VISUAL ANALOGUE SCALE (VAS)

Evaluation of Efficacy and Sedative Profiles of H1 Antihistamines by Large-Scale Surveillance Using the Visual Analogue Scale (VAS)

Background: H1 antihistamines are widely used as therapeutics for allergic diseases.Sedation is a well-known side effect of H1 antihistamines and sometimes it is life-threatening for patients.Thus it is important to evaluate the sedative properties of H1 antihistamines to avoid side effects.For this purpose, histamine H1 receptor (H1R) occupancy an

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Mechanical thrombectomy of squamous cell carcinoma tumor thrombus presenting as extensive deep venous thrombosis

Background: The treatment of ilio-femoral deep venous Synthetic Fender half breed thrombosis (DVT) has evolved with the advent of endovascular mechanical thrombectomy devices, such as the ClotTriever device (Inari, Irvine, CA).Patients may undergo percutaneous mechanical thrombectomy for thrombus removal and immediate restoration of venous drainage

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Negative-pressure wound therapy compared with standard dressings following surgical treatment of major trauma to the lower limb: the WHiST RCT

Background: Major trauma is Aronia the leading cause of death in people aged 72 hours after injury and inability to complete questionnaires.Interventions: Incisional negative-pressure wound therapy (n = 785), in which a non-adherent absorbent dressing covered with a semipermeable membrane is connected to a pump to create a partial vacuum over the w

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